If you don't have existing code, then just use the Ninja Coder Visual Studio Extension for MVVMCross [https://visualstudiogallery.msdn.microsoft.com/618b51f0-6de8-4f85-95ce-a50c658c7767] . If you have existing code already (ie: running an Xamarin android that you want to port to MvvmCross, then follow these steps: Creating New MvvmCross Project Setting